在线SDN控制器性能监控器设计与研究

随着网络规模和网络数据流量的变大,软件定义网络控制器性能问题可能成为网络瓶颈,为了在动态负载情况下仍然可以获取控制器准确的性能状态,设计了一个在线的性能监控器框架,并定义了控制器时延性能衡量指标Lpdex.在一款广泛使用的FloodLight控制器中实现了性能监控器的简单原型,经过实验评估,验证了控制器性能监控器的可行性和Lpdex可在线准确地反映控制器在不同负载情况下时延性能的变化.     

高精度多环片自动装配控制技术

为了实现对微小环片零件的自动化装配,搭建了自动装配系统.通过4根直线导向轴与4个直线轴承来提高系统的导向精度和刚度.采用直线导轨进行各装配作业模块之间的切换,保证了微小环片零件的自动装配与取出.在环片的装配方向上,螺旋升降机和光栅尺实现环片的位置精度控制.在Lab VIEW编程环境中,采用分层软件架构和模块化控制思想,避免了不必要的数据循环检测与丢失,能够达到环片组件的装配精度要求.控制系统分为系统初始化模块、参数设置模块、装配模块和取出模块,自动装配系统通过各个模块间的相互交流配合完成装配任务.采用本文中自动装配系统装配环片的实验结果表明,环片零件装配的最大位置误差为26μm,垂直度误差为17μm,平均装配时间为75 s/片,可满足环片组件所需的精度要求.     

Excited States and Photodebromination of Selected Polybrominated Diphenyl Ethers: Computational and Quantitative Structure—Property Relationship Studies

This paper presents a density functional theory (DFT)/time-dependent DFT (TD-DFT) study on the lowest lying singlet and triplet excited states of 20 selected polybrominateddiphenyl ether (PBDE) congeners, with the solvation effect included in the calculations using the polarized continuum model (PCM). The results obtained showed that for most of the brominated diphenyl ether (BDE) congeners, the lowest singlet excited state was initiated by the electron transfer from HOMO to LUMO, involving a π–σ* excitation. In triplet excited states, structure of the BDE congeners differed notably from that of the BDE ground states with one of the specific C–Br bonds bending off the aromatic plane. In addition, the partial least squares regression (PLSR), principal component analysis-multiple linear regression analysis (PCA-MLR), and back propagation artificial neural network (BP-ANN) approaches were employed for a quantitative structure-property relationship (QSPR) study. Based on the previously reported kinetic data for the debromination by ultraviolet (UV) and sunlight, obtained QSPR models exhibited a reasonable evaluation of the photodebromination reactivity even when the BDE congeners had same degree of bromination, albeit different patterns of bromination.     

CAT02 and HPE triangles

Here, we investigated the CAT02 and HPE triangles in both x,y and u′,v′ spaces. It was found that in u′,v′ space, the HPE triangle is separated into two regions by the line 3u′ ? 8v′ + 6 = 0, which is the u′,v′ image of X + Y + Z = 0 under the mapping from (X,Y,Z) to (u′,v′). One of these two regions admits all‐positive R,G,B triplets and the other all‐negative R,G,B triplets, under the case of (X + Y + Z) > 0. The findings of this study explained the computation problems of CAT02 and provided methods for solving the Yellow‐Blue and Purple problems simultaneously. © 2013 Wiley Periodicals, Inc. Col Res Appl, 40, 30–39, 2015     

Effects of different drying methods on the physicochemical property and edible quality of fermented Pyracantha fortuneana fruit powder

In this study, hot air drying (HAD), hot air-/microwave-assisted vacuum drying (HAMAVD) and hot air-assisted microwave drying (HAAMD) were applied to lactic acid-fermented Pyracantha fortuneana fruit (PFF). Influences of different drying methods on fluidity and dispersion, microstructure, hygroscopicity, rehydration, colour change, sourness and energy consumption were investigated. Results showed that HAAMD had the best overall performance on the quality of the PFF powder. HAAMD PFF powder had higher expansion force (1.65 mL g⁻¹) and water-holding capacity (2.68 g g⁻¹), lower degree of compression (9.09%) and energy consumption, smaller colour change and better taste. Organic acids (mainly malic acids) of all drying powders decreased, but HAAMD and HAMAVD could better improve the acidity characteristics of PFF powders, which may be related to the drying time and the temperature change processes. Consequently, this study can provide references for the utilisation of fresh PFF, the design and commercialisation of PFF-related products.     

Chemotherapy drugs derived nanoparticles encapsulating mRNA encoding tumor suppressor proteins to treat triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one type of the most aggressive breast cancers with poor prognosis. It is of great urgency to develop new therapeutics for treating TNBC. Based on current treatment guideline and genetic information of TNBC, a combinational therapy platform integrating chemotherapy drugs and mRNA encoding tumor suppressor proteins may become an efficacious strategy. In this study, we developed paclitaxel amino lipid (PAL) derived nanoparticles (NPs) to incorporate both chemotherapy drugs and P53 mRNA. The PAL P53 mRNA NPs showed superior properties compared to Abraxane^® and Lipusu^® used in the clinic including high paclitaxel loading capacity (24 wt.%, calculated by paclitaxel in PAL), PAL encapsulation efficiency (94.7% ± 6.8%) and mRNA encapsulation efficiency (88.7% ± 0.7%). Meanwhile, these NPs displayed synergetic cytotoxicity of paclitaxel and P53 mRNA in cultured TNBC cells. More importantly, we demonstrated in vivo anti-tumor efficacy of PAL P53 mRNA NPs in an orthotopic TNBC mouse model. Overall, these chemotherapy drugs derived mRNA NPs provide a new platform to integrate chemotherapy and personalized medicine using tumor genetic information, and therefore represent a promising approach for TNBC treatment.

     

Effect of Ladle Changeover Condition on Transient Three-Phase Flow in a Five-Strand Bloom Casting Tundish

Metallurgical and Materials Transactions B - The transient three-phase flow behavior in a five-strand bloom casting tundish during the ladle changeover process considering a constant casting speed...     

空间语义增强下的城市交通事故数据可视分析

目的 海量城市交通事故数据可能蕴含有交通事故的空间模式，挖掘出交通事故的空间模式有助于开展交通事故的防治工作。目前交通管理部门虽然记录了交通事故发生地的空间位置信息，但没有对事故发生地进行空间语义描述，从而影响对交通事故空间模式的深入分析。因此，提出一种交通事故数据空间语义增强方法，并设计了一套可视分析系统。方法 基于城市兴趣点来增强交通事故数据的空间语义。以事故发生点为中心获取周围城市兴趣点，使用特征向量刻画兴趣点的数量、类别及其与事故发生点的距离，并称此向量为空间语义特征向量。将空间语义特征向量和相应的交通事故关联，以达到增强其空间语义的目的。然后，基于空间语义特征向量，使用自组织映射聚类算法对交通事故进行聚类分析，根据其空间语义特征将交通事故分为若干类别。最后，通过使用地图视图展示事故点数据、聚类视图和平行坐标视图展示聚类分析的结果及其空间语义特征的可视化方法，对交通事故的空间模式进行分析。结果 针对空间语义增强的交通事故数据以及相关分析任务，有效地使用上述数据分析方法与可视化技术，设计并实现了一套多视图关联的可视分析系统，提供了便捷的交互方式辅助用户分析。通过研发人员和交通警察共同对安徽省合肥市2018年的交通事故数据进行分析，将交通事故发生地划分9类并指出每类地点的空间语义特点，进一步分析出了事故高发区域的空间语义特性。结论 本文提出的交通事故数据空间语义增强方法和可视分析方法可以帮助用户揭示交通事故的空间语义模式，有助于深入分析和认识交通事故的成因，能为交通事故防治相关的城市建设工作提供建议。